Anxiety Evaluation Scale for Autistic Children, as Reported by Parents, Shows Superior Performance Compared to Other Anxiety Assessment Methods
The Child Anxiety Impact Scale, Parent Version (CAIS-P) has been identified as a more accurate tool for detecting treatment outcomes in autistic children with anxiety disorders, according to a study published in Autism in 2025 by researchers led by Huilin Chen[1][2].
In the study, the CAIS-P outperformed other commonly used parent-report anxiety scales in identifying whether autistic children had recovered from anxiety following treatment. The CAIS-P was found to capture meaningful changes in anxiety impact after treatment better than alternative parent-report questionnaires, making it a valuable tool in both clinical settings and research involving autistic children[1].
The research involved 167 autistic children aged 7–13 who took part in a randomized controlled trial and had an autism diagnosis, an IQ above 70, and clinically significant anxiety[1]. Alongside the Anxiety Disorders Interview Schedule with Autism Spectrum Addendum (ADIS/ASA), parents completed four commonly used anxiety measures: the CAIS-P, the Paediatric Anxiety Rating Scale (PARS), the Child Behavior Checklist (CBCL) Anxious/Depressed subscale, and the Multidimensional Anxiety Scale for Children, Parent Version (MASC-P)[1].
The CAIS-P showed particularly high diagnostic accuracy in girls, suggesting it may be especially sensitive to changes in anxiety among autistic females[1]. In contrast, other measures in the study had AUC values well below the commonly accepted threshold of 0.7, indicating limited diagnostic usefulness in this context[1].
The CAIS-P differs from other tools as it measures the extent to which anxiety interferes with a child's daily life across school, social, and family settings, rather than simply counting symptoms[1]. This approach provides a clearer picture of meaningful clinical change for autistic children by focusing on how anxiety disrupts everyday activities.
However, the study did not test autism-specific anxiety scales, which may perform differently[1]. Additionally, the findings apply specifically to post-treatment assessments and do not indicate whether the CAIS-P is effective at detecting anxiety in community settings or over longer periods of time[1].
The CAIS-P had an area under the curve (AUC) of 0.802, indicating good performance in distinguishing between children who had and had not recovered from anxiety[1]. However, this result was based on imputed data and requires further investigation[1].
Anxiety is one of the most common mental health conditions among children with autism, with estimates suggesting that up to 40% of autistic children experience diagnosable anxiety problems[1]. The CAIS-P's ability to accurately detect treatment outcomes offers a significant step forward in addressing these challenges and improving the lives of autistic children.
In conclusion, the CAIS-P is considered a more precise and sensitive parent-report tool to monitor anxiety treatment outcomes in autistic children than other widely used scales, addressing the challenge of distinguishing anxiety symptoms from core autism features[1][2]. This makes it especially useful for ongoing treatment planning and outcome evaluation.
[1] Chen, H., et al. (2025). Accuracy of parent-report anxiety scales in detecting treatment outcomes in autistic children: A comparison of the Child Anxiety Impact Scale, Parent Version, and other commonly used measures. Autism, 29(3), 636-648. [2] Chen, H., et al. (2025). The Child Anxiety Impact Scale, Parent Version: A promising tool for assessing treatment outcomes in autistic children with anxiety disorders. Journal of Autism and Developmental Disorders, 45(5), 1503-1511.
- The study published in Autism in 2025 by Huilin Chen et al. emphasized the importance of the Child Anxiety Impact Scale, Parent Version (CAIS-P) in detecting treatment outcomes for autistic children with anxiety disorders.
- The CAIS-P outperformed other commonly used anxiety scales, revealing improvements in children's anxiety levels after treatment.
- In the study, 167 autistic children aged 7–13 participated in a randomized controlled trial and used the CAIS-P, among other anxiety measures.
- The CAIS-P was found to have high diagnostic accuracy, particularly in girls, suggesting it may be more sensitive to changes in anxiety among autistic females.
- Other measures in the study had limited diagnostic usefulness, with AUC values well below the commonly accepted threshold of 0.7.
- The CAIS-P measures the impact of anxiety on a child's daily life across various settings, providing a clearer picture of clinical change.
- Although the study did not test autism-specific anxiety scales, it highlights the value of the CAIS-P as a parent-report tool for ongoing treatment planning and outcome evaluation.
- Further investigation is required to understand the CAIS-P's performance based on imputed data.
- Anxiety is one of the most prevalent mental health conditions among children with autism, affecting up to 40% of them.
- The ability of the CAIS-P to precisely detect treatment outcomes offers a significant advancement in addressing these challenges and improving the lives of autistic children.
- Mental health professionals may find the CAIS-P valuable in mental health, psychology, education-and-self-development, and career-development fields.
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