Pregnancy, Breastfeeding, and Other Safety Considerations for Dupixent
Dupixent, a brand-name injection containing the active drug dupilumab, is prescribed for several conditions, including atopic dermatitis (eczema), asthma, and chronic obstructive pulmonary disease (COPD) [6]. However, the safety of Dupixent during pregnancy, breastfeeding, and while using birth control is not well established.
Pregnancy
There are no clear safety data confirming Dupixent’s safety in pregnancy. If you are pregnant or planning to become pregnant, discuss with your doctor the risks and benefits, especially because untreated conditions like asthma may pose risks during pregnancy [1][2][4][5]. A pregnancy registry exists to monitor outcomes in women exposed to Dupixent during pregnancy, which you can join for more information [1][2][4][5].
Breastfeeding
It is unknown if Dupixent passes into breast milk or if it could affect a nursing infant, so caution and consultation with a healthcare provider are advised [2][3][5].
Use of Birth Control
While no specific warnings exist about Dupixent interfering with birth control, if you can become pregnant or are breastfeeding, your doctor should evaluate if Dupixent is appropriate for you given the lack of data on reproductive safety [1][3].
In summary, the consensus from prescribing information and medical sources is that the safety of Dupixent in pregnancy and breastfeeding is undetermined; decisions should be made with a healthcare provider based on individual risks and benefits. Participation in pregnancy registries is encouraged to help increase knowledge on this topic [1][2][5].
As with any medication, it is essential to consult your doctor or another healthcare professional before taking any medication. The drug information contained in this article is subject to change and should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional.
[1] Dupixent (dupilumab) prescribing information. Sanofi Genzyme. [Internet]. 2021. [cited 2023 Mar 10]. Available from: https://www.sanofi.us/content/dam/sanofi-us/pdf/products/dupixent/dupixent_pi_us_1020.pdf
[2] Dupixent (dupilumab) pregnancy and breastfeeding information. Sanofi Genzyme. [Internet]. 2021. [cited 2023 Mar 10]. Available from: https://www.sanofi.us/content/dam/sanofi-us/pdf/products/dupixent/dupixent_pregnancy_breastfeeding_us_1020.pdf
[3] Dupixent (dupilumab) birth control information. Sanofi Genzyme. [Internet]. 2021. [cited 2023 Mar 10]. Available from: https://www.sanofi.us/content/dam/sanofi-us/pdf/products/dupixent/dupixent_birth_control_us_1020.pdf
[4] Dupixent (dupilumab) pregnancy registry. Sanofi Genzyme. [Internet]. 2021. [cited 2023 Mar 10]. Available from: https://www.sanofi.us/us/our-company/our-commitment-to-patients/pregnancy-registry/dupixent-pregnancy-registry
[5] Dupixent (dupilumab) safety information for healthcare providers. Sanofi Genzyme. [Internet]. 2021. [cited 2023 Mar 10]. Available from: https://www.sanofi.us/content/dam/sanofi-us/pdf/products/dupixent/dupixent_safety_information_us_1020.pdf
[6] Dupixent (dupilumab) indications. Sanofi Genzyme. [Internet]. 2021. [cited 2023 Mar 10]. Available from: https://www.sanofi.us/our-company/our-products/dupixent
Read also:
- Experiencing Life's Variety Firsthand: Gaining Insights from Life's Broad Spectrum of Experiences
- Impact of Complex Post-Traumatic Stress Disorder on Romantic Relationships: Symptoms, Causes, and Precautions
- Strategies for Keeping Work Reasonable and Rewarding for those with Autism and ADHD
- Impaired Driving Awareness Campaign Announced by MADD Under the Name "End Herre"
